Austin Meyer, MD, PhD, MPH, MS bio photo

Austin Meyer, MD, PhD, MPH, MS

Resident Physician at the Ohio State University and National Children's Hospital

Email Twitter LinkedIn Github
Google Scholar

Publications

2016    2015    2014    2013    2012    Before 2012    Opinion    Talks    Posters   


Peer Reviewed

    2017

  1. R. Rajmohan, R. C. Anderson, D. Fang, A. G. Meyer, P. Laengvejkal, P. Julayanont, G. Hannabas, K. Linton, J. Culberson, H. M. R. Khan, J. DeToledo, P. H. Reddy, M. O’Boyle (2017). White matter deterioration may foreshadow impairment of emotional valence determination in early-stage dementia of the alzheimer type. Frontiers in Aging Neuroscience 9:37.
    doi: 10.3389/fnagi.2017.00037  

  2. 2016

  3. C. D. McWhite, A. G. Meyer, C. O. Wilke (2016). Serial passaging causes extensive positive selection in seasonal influenza A hemagglutinin. Virus Evolution 2:vew026.
    doi: 10.1093/ve/vew026  

  4. B. R. Jack, A. G. Meyer, J. Echave, C. O. Wilke (2016). Functional sites induce long-range evolutionary constraints in enzymes. PLOS Biology 14:e1002452.
    doi: 10.1371/journal.pbio.1002452  

  5. 2015

  6. S. A. Kerr, E. L. Jackson, O. I. Lungu, A. G. Meyer, A Demogines, A. D. Ellington, G. Georgiou, C. O. Wilke, S. L. Sawyer (2015). Computational and functional analysis of the GP1-TfR1 interface reveals host range trade-offs in New-World arenaviruses. Journal of Virology 89:11643-11653.
    doi: 10.1128/JVI.01408-15  

  7. A. G. Meyer, C. O. Wilke (2015). The utility of protein structure as a predictor of site-wise dN/dS varies widely among HIV-1 proteins. Journal of the Royal Society Interface 12:20150579.
    doi: 10.1098/rsif.2015.0579  

    links: pre-print blog post  

  8. A. G. Meyer, S. J. Spielman, T. Bedford, C. O. Wilke (2015). Time dependence of evolutionary metrics during the 2009 pandemic influenza virus outbreak. Virus Evolution 1:vev006.
    doi: 10.1093/ve/vev006  

  9. A. G. Meyer, C. O. Wilke (2015). Geometric constraints dominate the antigenic evolution of influenza H3N2 hemagglutinin. PLOS Pathogens 11:e1004940.
    doi: 10.1371/journal.ppat.1004940  

  10. A. H. Kachroo, J. M. Laurent, C. M. Yellman, A. G. Meyer, C. O. Wilke, E. M. Marcotte (2015). Systematic humanization of yeast genes reveals conserved functions and genetic modularity. Science 348:921-925.
    doi: 10.1126/science.aaa0769  

    links: Press coverage by NPR, NBC News, Washington Post, Discovery News, Phys.org, The Scientist, Science Daily, Science News, Reddit, and others  

  11. 2014

  12. V. Sridhara, A. G. Meyer, P. Rai, J. E. Barrick, P. Ravikumar, D. Segrè, C. O. Wilke (2014). Predicting growth conditions from internal metabolic fluxes in an in-silico model of E. coli. PLOS ONE 9:e114608.
    doi: 10.1371/journal.pone.0114608  

  13. J. E. Barrick, G. Colburn, D. E. Deatherage, C. C. Traverse, M. D. Strand, J. J Borges, D. D. Knoester, A. Reba, A. G. Meyer (2014). Identifying structural variation in haploid microbial genomes from short-read re-sequencing data using breseq. BMC Genomics 15:1039.
    doi: 10.1186/1471-2164-15-1039  

  14. A. Shahmoradi, D. K. Sydykova, S. J. Spielman, E. L. Jackson, E. T. Dawson, A. G. Meyer, C. O. Wilke (2014). Predicting evolutionary site variability from structure in viral proteins: buriedness, packing, flexibility, and design. J. Mol. Evol. 79:130–142.
    doi: 10.1007/s00239-014-9644-x  

  15. A. G. Meyer, S. L. Sawyer, A. D. Ellington, C. O. Wilke (2014). Analyzing Machupo virus-receptor binding by molecular dynamics simulations. PeerJ 2:e266.
    doi: 10.7717/peerj.266  
    pmcid: PMC3940602  

  16. K. Fuson, A. Rice, R. Mahling, A. Snow, K. Nayak, P. Shanbhogue, A. G. Meyer, G. Redpath, A. Hinderliter, S. T. Cooper, R. B. Sutton (2014). Alternate splicing of dysferlin C2A confers Ca2+-dependent and Ca2+-independent binding for membrane repair. Structure 22:104-115.
    doi: 10.1016/j.str.2013.10.001  
    pmcid: PMC24239457  

  17. 2013

  18. M. Z. Tien, A. G. Meyer, D. K. Sydykova, S. J. Spielman, C. O. Wilke (2013). Maximum allowed solvent accessibilites of residues in proteins. PLOS ONE 8:e80635.
    doi: 10.1371/journal.pone.0080635  
    pmcid: PMC3836772  

  19. M. Z. Tien, D. K. Sydykova, A. G. Meyer, C. O. Wilke (2013). PeptideBuilder: A simple Python library to generate model peptides. PeerJ 1:e80.
    doi: 10.7717/peerj.80  
    pmcid: PMC3661355  

  20. A. G. Meyer, E. T. Dawson, C. O. Wilke (2013). Cross-species comparison of site-specific evolutionary-rate variation in influenza haemagglutinin. Phil. Trans. R. Soc. B. 368:20120334.
    doi: 10.1098/rstb.2012.0334  
    pmcid: PMC3678335  

  21. A. G. Meyer, C. O. Wilke (2013). Integrating sequence variation and protein structure to identify sites under selection. Mol. Biol. Evol. 30:36–44.
    doi: 10.1093/molbev/mss217  
    pmcid: PMC3525147  

  22. 2012

  23. M. P. Scherrer, A. G. Meyer, C. O. Wilke (2012). Modeling coding-sequence evolution within the context of residue solvent accessibility. BMC Evol. Biol. 12:179.
    doi: 10.1186/1471-2148-12-179  
    pmcid: PMC3527230  

  24. A. Reba, A. G. Meyer, J. E. Barrick (2012). Computational tests of a thermal cycling strategy to isolate more complex functional nucleic acid motifs from random sequence pools by in vitro selection. Artificial Life 13:473–480.
    doi: 10.7551/978-0-262-31050-5-ch062  

  25. Before 2012

  26. Y. G. Celebi, R. L. Lichti, H. N. Bani-Salameh, A. G. Meyer, B. R. Carroll, J. E. Vernon, P. J. C. King, S. F. J. Cox. Muonium transitions in 4H silicon carbide. Physica B 404:845-884.
    doi: 10.1016/j.physb.2008.11.155  

  27. H. N. Bani-Salameh, A. G. Meyer, B. R. Carroll, R. L. Lichti, K. H. Chow, P. J. C. King, S. F. J. Cox. Charge-state transitions of muonium in 6H silicon carbide. Physica B 401-402:631-634.
    doi: 10.1016/j.physb.2007.09.039  

Opinion

  1. A. G. Meyer (2016). Analysis of infection biomarkers within a Bayesian framework reveals their role in pneumococcal pneumonia diagnosis in HIV patients. bioRxiv.
    doi: 10.1101/070144  

  2. S. J. Spielman, A. G. Meyer, C. O. Wilke (2014). Increased evolutionary rate in the 2014 West African Ebola outbreak is due to transient polymorphism and not positive selection. bioRxiv.
    doi: 10.1101/011429  

  3. R. E. Solnick, A. G. Meyer (2014). Law should allow physicians to use their judgement. Texas Medicine, 110:11-12.

Invited Talks

  1. A. G. Meyer (2015). PDB's, protein structure and dynamics. Computational Biology Course, University of Texas at Austin.

  2. A. G. Meyer (2014). Simulating the evolution of protein-protein interactions. AG3C Seminar, University of Texas at Austin.

Poster Presentations

  1. A. G. Meyer, B. R. Jack, J. Echave C. O. Wilke (2016). Functional sites induce long-range evolutionary constraints in enzymes. Student Research Week, Graduate School of Biomedical Sciences and School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX.

  2. A. G. Meyer, C. O. Wilke (2015). Geometric constraints dominate the antigenic evolution of influenza H3N2 hemagglutinin. Student Research Week, Graduate School of Biomedical Sciences and School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX.

  3. S. J. Spielman, A. G. Meyer, C. O. Wilke (2015). Apparent increased evolutionary rate in the 2014 West African Ebola outbreak signals transient polymorphism and not positive selection. Ebola Modeling Workshop, Georgia Institute of Technology, Atlanta, GA. Invited

  4. A. G. Meyer, C. O. Wilke (2014). Analyzing Machupo virus-receptor binding by molecular dynamics simulation. Student Research Week, Graduate School of Biomedical Sciences and School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX. Awarded Best Presentation

  5. F. S. Thomas, A. G. Meyer, S. A. Hattenbach, L. K. Tollack, D. T. Vu, M. Hong, K. Bennett, F. Prabhu (2014). Population characteristics and medical treatment of blood pressure at the Free Clinic. Student Research Week, Graduate School of Biomedical Sciences and School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX.

  6. A. G. Meyer, C. O. Wilke (2014). Analyzing Machupo virus-receptor binding by molecular dynamics simulation. Biophysical Society Annual Meeting, San Francisco, CA..

  7. A. G. Meyer, F. S. Thomas, S. A. Hattenbach, L. K. Tollack, D. T. Vu, M. Hong, K. Bennett, F. Prabhu (2014). Effectiveness of medical treatment of blood pressure at the TTUHSC Free Clinic. Society for Student Run Free Clinics Annual Meeting, Nashville, TN.

  8. F. S. Thomas, A. G. Meyer, S. A. Hattenbach, L. K. Tollack, D. T. Vu, M. Hong, K. Bennett, F. Prabhu (2014). Effectiveness of medical treatment of type 2 diabetes at the TTUHSC Free Clinic. Society for Student Run Free Clinics Annual Meeting, Nashville, TN.

  9. A. G. Meyer, E. T. Dawson, C. O. Wilke (2013). Cross-species comparison of site-specific evolutionary-rate variation in influenza hemagglutinin. Student Research Week, Graduate School of Biomedical Sciences and School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX.

  10. A. G. Meyer, C. O. Wilke (2012). Combining protein structure and sequence variation to identify functionally important sites. Society for Molecular Biology and Evolution Annual Meeting, Dublin, Ireland.

  11. K. L. Fuson, A. G. Meyer, K. Knutson, J. W. Gauer, J. Murphy, A. F. Oberhauser, A. Hinderliter, R. B. Sutton (2010). A link between structure and cooperativity in the C2A domain of Synaptotagmin 1. Biophysical Society Annual Meeting, San Francisco, CA.

  12. A. G. Meyer, N. Quissenberry, K. Fuson, R. B. Sutton (2010). Functional relevance of mutations and truncations in Dysferlin and Synaptotagmin 1. Graduate School and Biomedical Sciences Annual Retreat, Texas Tech University Health Sciences Center, Lubbock, TX.

  13. A. G. Meyer, N. Quisenberry, K. Fuson, R. B. Sutton (2009). Cardiomyopathy caused by structural instability in Dysferlin C2 domains. Implications for LGMD2B and CABG. Center for Cardiovascular Disease and Stroke Symposium, Texas Tech University Health Sciences Center, Lubbock, TX.